Rise of New CRISPR Inventions: the toolbox of research applications for CRISPR-based systems continues to expand

Daniel Lim

Although much of the reporting around CRISPR tends to focus on its cleavage based ability to knock out or repair targeted sequences of DNA in a genome, some of the most exciting developments in the CRISPR field do not involve gene editing at all. Many of these advances are already being put into effect in basic science research, molecular diagnostics and drug discovery. DETECTR, CAMERA and SHERLOCK are the acronyms that researchers have given some of the latest of these diagnostic manifestations of CRISPR technology, which are being developed by some of the leading lights in the field.

This article profiles the science and significance of these new CRISPR-based tools.

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